St. Francis De Sales School is located in Guwahati, the largest city in Assam and the principal metropolis of North-East India, situated on the banks of the river Brahmaputra. Its strategic location enables the school to attract bright and talented students from across the city, fostering a diverse and vibrant learning community. With a strong commitment to academic excellence and inclusivity, the school strives to provide fair and equitable quality education, preparing students to thrive in a global society.

Spread across 3.08 acres, the school offers state-of-the-art infrastructure, including well-equipped science and computer laboratories, smart classrooms, sports and games facilities, music and dance rooms, health check-up facilities, and a Wi-Fi-enabled campus. A warm and interactive teacher–student environment makes learning joyful, while continuous and comprehensive evaluation ensures the holistic development of every learner.